Pioneering Innovation in Oral Healthcare and Nutrition
- \Discover our new vitamin delivery system
- \Revolutionise your oral health
- \Give back through our humanitarian impact mission
Pioneering Innovation in Oral Healthcare and Nutrition
- \Discover our new vitamin delivery system
- \Revolutionise your oral health
- \Give back through our humanitarian impact mission
Invested in by the Oxford Seed Fund
Winner, Hauge Business Network Idea Competition
Winner, Oxford Foundry All-Innovate Best Graduate Idea
Winner, Social Enterprise Awards, Oxford Hub
Winner, Oxford Impact Award for Enterprise and Innovation
Invested in by the Oxford Seed Fund
Winner, Hauge Business Network Idea Competition
Winner, Oxford Foundry All-Innovate Best Graduate Idea
Winner, Social Enterprise Awards, Oxford Hub
Winner, Oxford Impact Award for Enterprise and Innovation
Absorbed in the mouth, delivered straight into your bloodstream
An alternative to gut absorption
Vitaegum is absorbed in the mouth, as opposed to the gut which can be sensitive to a number of factors such as :
Common prescribed and over-the-counter medications
Many common medications can interfere with gut nutrient absorption. Mohn, E.S., Kern, H.J., Saltzman, E., Mitmesser, S.H. and McKay, D.L., 2018. Evidence of drug–nutrient interactions with chronic use of commonly prescribed medications: An update. Pharmaceutics, 10(1), p.36. Nutrient uptake can be influenced by:
- SSRI antidepressants
- Oral contraceptives
- Anti-hypertensives
- NSAIDs
IBS and digestive issues/diseases
Many gut diseases reduce nutrient absorption, which can lead to deficiencies over time. Narang, N. and Sharma, J., 2011. Sublingual mucosa as a route for systemic drug delivery. Int J Pharm Pharm Sci, 3,, pp.18-22. This includes people with
- IBS
- Crohn’s disease
- Coeliac disease
- Pernicious anaemia
- Ulcerative colitis
Harsh gastric conditions
Vitamins from food and conventional supplements have shown poor bioavailability due to harsh gastric conditions and the first pass effect of liver metabolism, as nutrients are broken down by metabolizing enzymes in the liver before it enters the systemic circulation. Bates, C. J., & Heseker, H., (1994). Human Bioavailability of Vitamins, Nutrition Research Reviews, 7, 93-127 Pawar PP, Ghorpade HS, Kokane BA, Sublingual route for systemic drug delivery, Journal of Drug Delivery and Therapeutics. 2018; 8(6-s):340-343 DOI: http://dx.doi.org/10.22270/jddt.v8i6-s.2097
The mucosal delivery system
The mouth is an ideal way to deliver micronutrients
Bitamins efficiently enter the systemic bloodstream directly through the closely-knit blood vessels throughout your mouth
The mouth is lined with mucosa, a moist membrane lining.
It is highly vascularised, with capillaries lying just beneath the surface.
Vitamins can diffuse across the thin mucosal membrane and 1 cell thick wall of the capillaries, directly into the bloodstream.
Quick and effective absorption
- Chewing (masticating) increases blood flow and stimulates the metabolism, optimising conditions for sublingual nutrient uptake. Miyake, S., Wada-Takahashi, S., Honda, H., Takahashi, S.S., Sasaguri, K. and Sato, S., 2012. Stress and chewing affect blood flow and oxygen levels in the rat brain. Archives of Oral Biology, 57(11), pp.1491-1497.
- Sublingual absorption alone (via the veins under the tongue) has been proven to increase substrate intake up to 10x Naimish, A.S., Vipul, P.P. and Devang, J.P., 2013. Sublingual delivery: a promising approach to improve bioavailability. Pharma Science Monitor, 4(2).
Sublingual absorption alone (via the veins under the tongue) has been proven to increase substrate intake up to 10x
Bitamins efficiently enter the systemic bloodstream directly through the closely-knit blood vessels throughout your mouth
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1 gum = 9 vitamins and minerals
2 gum = 100% RDA
Vitamin A
Important to the function of:
- Cell metabolism in the brain
- DNA synthesis and red bood cell production
- Extreme fatigue and weakness
- Depressive mental health conditions
2 gum = 100% RDA
Vitamin B1
Important to the function of:
- Healthy metabolism
- Energy for the body, especially the brain and nervous system
- Fatigue
- Muscle weakness
- Poor cognitive function
2 gum = 100% RDA
Vitamin B12
Important to the function of:
- Cell metabolism in the brain
- DNA synthesis and red bood cell production
- Extreme fatigue and weakness
- Depressive mental health conditions
2 gum = 100% RDA
Vitamin B2
Important to the function of:
- Energy yielding metabolism
- Breakdown of fats and medications
- Healthy skin and vision
- Cataracts
- Blood shot eyes
- Fatigue
2 gum = 100% RDA
Vitamin B6
Is important to the function of:
- Dopamine and serotonin
- The immune system
- Metabolism in cells
- Weak immune system
- Low mood
- Reduced cognitive abilities
2 gum = 100% RDA
Vitamin C
Is important to:
- The immune system
- Collagen production (healthy skin)
- Healthy blood vessels, bones and cartilage
- Uptake of iron
- Longer colds
- Slow wound healing
- Impaired immunity and Susceptibility to infections
2 gum = 100% RDA
Vitamin D
Important to the function of:
- The immune system
- Healthy teeth and bones
- Depression
- Susceptibility to infections
2 gum = 80% RDA
Iron
Is important to the function of:
- Metabolism
- Collagen production
- Cholesterol
- Weakness
- Headache, dizziness or lightheadedness
- Brittle nails
2 gum = 60% RDA
Zinc
Important to the function of:
- The immune system
- Metabolism and gut health
- Healthy brain function
- Night blindness
- Memory impairment
- Dermatitis
Cleans teeth
Chewing gum cleans teeth mechanically, helping remove food trapped between the teeth. Chewing gum after meals is correlated with better oral health.
Strenghtens enamel
Vitamin A and Xylitol contribute to strengthening and remineralising the dental enamel. Chewing gum also contributes to increased buffering agents and protein, linked to reduction in enamel erosion.
Kills bacteria
Xylitol directly inhibits growth of 90% of bacteria that cause cavities and gum disease. Vitaegum contains a number of other antimicrobial agents that kill the bacteria that cause bad breath, cavities and gum disease: Vitamin C, Xylitol, Zink, Vitamin A, D, and B12.
Prevents periodontal disease
Vitaegum contains antimicrobial ingredients that help reduce the bacteria that can lead to periodontal disease. Furthermore, it contains vitamins like Iron that are correlated with risk of periodontal disease.
Reduces plaque
Vitamin A is especially crucial, as even minor deficiency alters saliva production and makes it less efficient at reducing plaque acids. Vitamin C increases saliva, conteibuting to reducing tartar and plaque built-up.
Supports remineralisation
Several of the ingredients in Vitaegum help support remineralisation. For example, Vitamin D is important to tooth remineralisation by helping the body absorb calcium and phosphate, essential for remineralisation.
Healty gums
Vitamin B12 (Folic Acid) deficiency is linked to gingival bleeding of the gums. Vitamin C reduces inflammation in the gums, and deficiency can cause bleeding gums and scurvy.
Revolutionary oral health benefits
How our ingredients supports oral health:
Vitamin A
Plaque acid reduction Even mild vitamin A deficiencies can alter saliva production and make it less efficient at reducing plaque acids.
Rathee, M., Bhoria, D. and Kundu, D., 2011. Vitamin C and oral health: A review. Indian J Appl Res, 3, pp.462-3.
Maintaining strong tooth enamel Vitamin A is important for maintaining strong tooth enamel, oral cell lining development, and saliva production
Sheetal, A., Hiremath, V.K., Patil, A.G., Sajjansetty, S. and Kumar, S.R., 2013. Malnutrition and its oral outcome–a review. Journal of clinical and diagnostic research: JCDR, 7(1), p.178.
Immune defence in the oral cavity Vitamin A is involved in wound healing and immune defence in the oral cavity
Rathee, M., Bhoria, D. and Kundu, D., 2011. Vitamin C and oral health: A review. Indian J Appl Res, 3, pp.462-3.
Rathee, M., Bhoria, D. and Kundu, D., 2011. Vitamin C and oral health: A review. Indian J Appl Res, 3, pp.462-3.
Maintaining strong tooth enamel Vitamin A is important for maintaining strong tooth enamel, oral cell lining development, and saliva production
Sheetal, A., Hiremath, V.K., Patil, A.G., Sajjansetty, S. and Kumar, S.R., 2013. Malnutrition and its oral outcome–a review. Journal of clinical and diagnostic research: JCDR, 7(1), p.178.
Immune defence in the oral cavity Vitamin A is involved in wound healing and immune defence in the oral cavity
Rathee, M., Bhoria, D. and Kundu, D., 2011. Vitamin C and oral health: A review. Indian J Appl Res, 3, pp.462-3.
Vitamin B12
Prevent bleeding of gums Folic acid deficiency has been linked to gingival bleeding of the gums, which can point to inflamed and/or collagen deficient gums.
Prasad, A.S., Lei, K.Y., Moghissi, K.S., Stryker, J.C. and Oberleas, D., 1976. Effect of oral contraceptives on nutrients: III. Vitamins B6, B12, and folic acid. American Journal of Obstetrics and Gynecology, 125(8), pp.1063-1069.
Prevent dental caries Low or inadequate intake of Vitamin B12 is associated with increased caries.
Al Mashhadane, F.A. and Taqa, A.A.R., 2019. Vitamins and their relations to oral health: A review study. International Journal of Research Publications, 22(1), pp.3-16.
Prasad, A.S., Lei, K.Y., Moghissi, K.S., Stryker, J.C. and Oberleas, D., 1976. Effect of oral contraceptives on nutrients: III. Vitamins B6, B12, and folic acid. American Journal of Obstetrics and Gynecology, 125(8), pp.1063-1069.
Prevent dental caries Low or inadequate intake of Vitamin B12 is associated with increased caries.
Al Mashhadane, F.A. and Taqa, A.A.R., 2019. Vitamins and their relations to oral health: A review study. International Journal of Research Publications, 22(1), pp.3-16.
Vitamin C
Reduction of bacterial growth Increasing saliva levels of vit c decreases bacterial growth that causes dental caries
Eydou, Z., Jad, B.N., Elsayed, Z., Ismail, A., Magaogao, M. and Hossain, A., 2020. Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries. BMC microbiology, 20(1), pp.1-11.
Healthy gums and reduced risk of periodontal disease Vitamin D deficiency can lead to scurvy and bleeding gums. Vitamin D is important to the collagen required for periodontal ligament production, and contribute to reduce inflammation in the gums.
Murererehe, J., Uwitonze, A.M., Nikuze, P., Patel, J. and Razzaque, M.S., 2022. Beneficial Effects of Vitamin C in Maintaining Optimal Oral Health. Frontiers in Nutrition, 8, p.1245.
Reduce plaque built-up Lingström, P., Fure, S., Dinitzen, B., Fritzne, C., Klefbom, C. and Birkhed, D., 2005. The release of vitamin C from chewing gum and its effects on supragingival calculus formation. European journal of oral sciences, 113(1), pp.20-27.
Eydou, Z., Jad, B.N., Elsayed, Z., Ismail, A., Magaogao, M. and Hossain, A., 2020. Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries. BMC microbiology, 20(1), pp.1-11.
Healthy gums and reduced risk of periodontal disease Vitamin D deficiency can lead to scurvy and bleeding gums. Vitamin D is important to the collagen required for periodontal ligament production, and contribute to reduce inflammation in the gums.
Murererehe, J., Uwitonze, A.M., Nikuze, P., Patel, J. and Razzaque, M.S., 2022. Beneficial Effects of Vitamin C in Maintaining Optimal Oral Health. Frontiers in Nutrition, 8, p.1245.
Reduce plaque built-up Lingström, P., Fure, S., Dinitzen, B., Fritzne, C., Klefbom, C. and Birkhed, D., 2005. The release of vitamin C from chewing gum and its effects on supragingival calculus formation. European journal of oral sciences, 113(1), pp.20-27.
Vitamin D
Tooth remineralisation Vitamin D is important for tooth remineralisation and development. It helps the body absorb calcium and phosphate, essential for mineralisation.
Adegboye, A.R., Christensen, L.B., Holm-Pedersen, P., Avlund, K., Boucher, B.J. and Heitmann, B.L., 2013. Intakes of calcium, vitamin D, and dairy servings and dental plaque in older Danish adults. Nutrition Journal, 12, pp.1-5.
Prevent gingival inflammation Aranow, C., 2011. Vitamin D and the immune system. Journal of investigative medicine, 59(6), pp.881-886. Tomaz, M.R., Macit, M.S., Niza, M.I., Jeavons, C.A., Heitmman, B.L. and Amorim Adegboye, A.R., 2020. The effect of vitamin D and/or Calcium supplementation on periodontitis. International Journal of Food, Nutrition and Public Health, 11(1/2), pp.65-81. [/tooltip]
Adegboye, A.R., Christensen, L.B., Holm-Pedersen, P., Avlund, K., Boucher, B.J. and Heitmann, B.L., 2013. Intakes of calcium, vitamin D, and dairy servings and dental plaque in older Danish adults. Nutrition Journal, 12, pp.1-5.
Prevent gingival inflammation Aranow, C., 2011. Vitamin D and the immune system. Journal of investigative medicine, 59(6), pp.881-886. Tomaz, M.R., Macit, M.S., Niza, M.I., Jeavons, C.A., Heitmman, B.L. and Amorim Adegboye, A.R., 2020. The effect of vitamin D and/or Calcium supplementation on periodontitis. International Journal of Food, Nutrition and Public Health, 11(1/2), pp.65-81. [/tooltip]
Iron
Prevent periodontal diseaseAnemia caused by Iron is a risk factor for periodontal disease. The lack of oxygen in the gums due to anaemia can lead to gum disease and tooth loss.
Hatipoglu, H., Hatipoglu, M.G., Cagirankaya, L.B. and Caglayan, F., 2012. Severe periodontal destruction in a patient with advanced anemia: A case report. European journal of dentistry, 6(01), pp.095-100.
Hatipoglu, H., Hatipoglu, M.G., Cagirankaya, L.B. and Caglayan, F., 2012. Severe periodontal destruction in a patient with advanced anemia: A case report. European journal of dentistry, 6(01), pp.095-100.
Zinc
Reduction of bacteria Zinc acts as an antimicrobial, destroying bacteria responsible for plaque and cavity formation, as well as bad breath
Almoudi, M.M., Hussein, A.S., Abu Hassan, M.I. and Mohamad Zain, N., 2018. A systematic review on antibacterial activity of zinc against Streptococcus mutans. Saudi Dent J. 2018.
Combat plaque Zinc is used to combat plaque, reduce malodour and inhibit plaque formation. It is frequently found in mouthwashes and toothpastes.
Lynch, R.J., 2011. Zinc in the mouth, its interactions with dental enamel and possible effects on caries; a review of the literature. International dental journal, 61, pp.46-54.
Treats ulcers, periodontitis and cavities Lynch, R.J., 2011. Zinc in the mouth, its interactions with dental enamel and possible effects on caries; a review of the literature. International dental journal, 61, pp.46-54.
Promote healthy gums Uwitonze, A.M., Ojeh, N., Murererehe, J., Atfi, A. and Razzaque, M.S., 2020. Zinc adequacy is essential for the maintenance of optimal oral health. Nutrients, 12(4), p.949.
Almoudi, M.M., Hussein, A.S., Abu Hassan, M.I. and Mohamad Zain, N., 2018. A systematic review on antibacterial activity of zinc against Streptococcus mutans. Saudi Dent J. 2018.
Combat plaque Zinc is used to combat plaque, reduce malodour and inhibit plaque formation. It is frequently found in mouthwashes and toothpastes.
Lynch, R.J., 2011. Zinc in the mouth, its interactions with dental enamel and possible effects on caries; a review of the literature. International dental journal, 61, pp.46-54.
Treats ulcers, periodontitis and cavities Lynch, R.J., 2011. Zinc in the mouth, its interactions with dental enamel and possible effects on caries; a review of the literature. International dental journal, 61, pp.46-54.
Promote healthy gums Uwitonze, A.M., Ojeh, N., Murererehe, J., Atfi, A. and Razzaque, M.S., 2020. Zinc adequacy is essential for the maintenance of optimal oral health. Nutrients, 12(4), p.949.
Xylitol
Prevents demineralisation and supports remineralisation Imran, F. and Amr, B., 2021. The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review. F1000Research, 9.
irectly inhibits growth of 90% of bacteria that cause cavities Han, S.J., Jeong, S.Y., Nam, Y.J., Yang, K.H., Lim, H.S. and Chung, J., 2005. Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical and Vaccine Immunology, 12(11), pp.1285-1291
Reduce acid plaque formatio Imran, F. and Amr, B., 2021. The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review. F1000Research, 9.
irectly inhibits growth of 90% of bacteria that cause cavities Han, S.J., Jeong, S.Y., Nam, Y.J., Yang, K.H., Lim, H.S. and Chung, J., 2005. Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical and Vaccine Immunology, 12(11), pp.1285-1291
Reduce acid plaque formatio Imran, F. and Amr, B., 2021. The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review. F1000Research, 9.
Chewing gum
Removes food trapped between teeth Dawes, C., Pedersen, A.L., Villa, A., Ekström, J., Proctor, G.B., Vissink, A., Aframian, D., McGowan, R., Aliko, A., Narayana, N. and Sia, Y.W., 2015. The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI. Archives of oral biology, 60(6), pp.863-874.
Reduction in enamel erosion Chewing gum increase saliva production, which acts as a buffer for acidic plaque, thus preventing demineralisation.
Dawes, C., Pedersen, A.L., Villa, A., Ekström, J., Proctor, G.B., Vissink, A., Aframian, D., McGowan, R., Aliko, A., Narayana, N. and Sia, Y.W., 2015. The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI. Archives of oral biology, 60(6), pp.863-874.
Reduce occurrence of cavities when eaten after meals Claxton, L., Taylor, M. and Kay, E., 2016. Oral health promotion: the economic benefits to the NHS of increased use of sugarfree gum in the UK. British dental journal, 220(3), pp.121-127.Mickenautsch, S., Leal, S.C., Yengopal, V., Bezerra, A.C. and Cruvinel, V., 2007. Sugar-free chewing gum and dental caries: a systematic review. Journal of Applied Oral Science, 15, pp.83-88.Manning, R.H. and Edgar, W.M., 1993. pH changes in plaque after eating snacks and meals, and their modification by chewing sugared-or sugar-free gum. British dental journal, 174(7), pp.241-244.
Reduction in enamel erosion Chewing gum increase saliva production, which acts as a buffer for acidic plaque, thus preventing demineralisation.
Dawes, C., Pedersen, A.L., Villa, A., Ekström, J., Proctor, G.B., Vissink, A., Aframian, D., McGowan, R., Aliko, A., Narayana, N. and Sia, Y.W., 2015. The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI. Archives of oral biology, 60(6), pp.863-874.
Reduce occurrence of cavities when eaten after meals Claxton, L., Taylor, M. and Kay, E., 2016. Oral health promotion: the economic benefits to the NHS of increased use of sugarfree gum in the UK. British dental journal, 220(3), pp.121-127.Mickenautsch, S., Leal, S.C., Yengopal, V., Bezerra, A.C. and Cruvinel, V., 2007. Sugar-free chewing gum and dental caries: a systematic review. Journal of Applied Oral Science, 15, pp.83-88.Manning, R.H. and Edgar, W.M., 1993. pH changes in plaque after eating snacks and meals, and their modification by chewing sugared-or sugar-free gum. British dental journal, 174(7), pp.241-244.